Chronic myeloid leukaemia (CML) affects a type of white blood cell called a myeloid cell.
In particular, it involves a type of myeloid cell called a granulocyte; as a result, you may also hear it called chronic granulocytic leukaemia, or CGL. Over time, these abnormal white blood cells fill the bone marrow, reducing the number of normal white blood cells, red blood cells and platelets that are made.
CML is a rare cancer; only around 700 people are diagnosed in the UK each year.
There are different phases of chronic myeloid leukaemia: the chronic phase, accelerated phase and blast phase. There are different treatment options for each phase. In the chronic phase, your doctors would normally only discuss a bone marrow or stem cell transplant with you if the CML hasn’t responded to other treatments.
A transplant might be a treatment option if you have CML that is in an accelerated or blast phase after you’ve already received a type of medicine called a cancer growth blocker (or TKI).
Transplants for CML are allograft transplants – when your new stem cells are donated by someone else.